Bioinformatics tools for marine biotechnology: a practical tutorial with a metagenomic approach.

ABSTRACT:

Background

Bioinformatics has pervaded all fields of biology and has become an indispensable tool for almost all research projects. Although teaching bioinformatics has been incorporated in all traditional life science curricula, practical hands-on experiences in tight combination with wet-lab experiments are needed to motivate students.

Results

We present a tutorial that starts from a practical problem: finding novel enzymes from marine environments. First, we introduce the idea of metagenomics, a recent approach that extends biotechnology to non-culturable microbes. We presuppose that a probe for the screening of metagenomic cosmid library is needed. The students start from the chemical structure of the substrate that should be acted on by the novel enzyme and end with the

SUBMITTER: Liguori L 

PROVIDER: S-EPMC7447578 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature