Rapid establishment of a COVID-19 perinatal biorepository: early lessons from the first 100 women enrolled.

ABSTRACT:

Background

Collection of biospecimens is a critical first step to understanding the impact of COVID-19 on pregnant women and newborns - vulnerable populations that are challenging to enroll and at risk of exclusion from research. We describe the establishment of a COVID-19 perinatal biorepository, the unique challenges imposed by the COVID-19 pandemic, and strategies used to overcome them.

Methods

A transdisciplinary approach was developed to maximize the enrollment of pregnant women and their newborns into a COVID-19 prospective cohort and tissue biorepository, established on March 19, 2020 at Massachusetts General Hospital (MGH). The first SARS-CoV-2 positive pregnant woman was enrolled on April 2, and enrollment was expanded to SARS-CoV-2 negative controls on April 20. A

SUBMITTER: Shook LL 

PROVIDER: S-EPMC7447612 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature