Metabolome of canine and human saliva: a non-targeted metabolomics study.

ABSTRACT:

Introduction

Saliva metabolites are suggested to reflect the health status of an individual in humans. The same could be true with the dog (Canis lupus familiaris), an important animal model of human disease, but its saliva metabolome is unknown. As a non-invasive sample, canine saliva could offer a new alternative material for research to reveal molecular mechanisms of different (patho)physiological stages, and for veterinary medicine to monitor dogs' health trajectories.

Objectives

To investigate and characterize the metabolite composition of dog and human saliva in a non-targeted manner.

Methods

Stimulated saliva was collected from 13 privately-owned dogs and from 14 human individuals. We used a non-targeted ultra-high-performance liquid chromatography-quadrupole t

SUBMITTER: Turunen S 

PROVIDER: S-EPMC7447669 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature