Spatially selective manipulation of cells with single-beam acoustical tweezers.

ABSTRACT: Acoustical tweezers open major prospects in microbiology for cells and microorganisms contactless manipulation, organization and mechanical properties testing since they are biocompatible, label-free and have the potential to exert forces several orders of magnitude larger than their optical counterpart at equivalent power. Yet, these perspectives have so far been hindered by the absence of spatial selectivity of existing acoustical tweezers - i.e., the ability to select and move objects individually - and/or their limited resolution restricting their use to large particle manipulation only and/or finally the limited forces that they could apply. Here, we report precise selective manipulation and positioning of individual human cells in a standard microscopy environment with trapping force

SUBMITTER: Baudoin M 

PROVIDER: S-EPMC7447757 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature