Timing of Intubation and Mortality Among Critically Ill Coronavirus Disease 2019 Patients: A Single-Center Cohort Study.

ABSTRACT:

Objectives

Increasing time to mechanical ventilation and high-flow nasal cannula use may be associated with mortality in coronavirus disease 2019. We examined the impact of time to intubation and use of high-flow nasal cannula on clinical outcomes in patients with coronavirus disease 2019.

Design

Retrospective cohort study.

Setting

Six coronavirus disease 2019-specific ICUs across four university-affiliated hospitals in Atlanta, Georgia.

Patients

Adults with laboratory-confirmed severe acute respiratory syndrome coronavirus 2 infection who received high-flow nasal cannula or mechanical ventilation.

Interventions

None.

Measurements and main results

Among 231 patients admitted to the ICU, 109 (47.2%) were treated with high-flow nasal cannula and 97

SUBMITTER: Hernandez-Romieu AC 

PROVIDER: S-EPMC7448713 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature