A three-lncRNA signature of pretreatment biopsies predicts pathological response and outcome in esophageal squamous cell carcinoma with neoadjuvant chemoradiotherapy.

ABSTRACT:

Background

Current strategies are insufficient to predict pathologically complete response (pCR) for esophageal squamous cell carcinomas (ESCCs) before treatment. Here, we aim to develop a novel long noncoding RNA (lncRNA) signature for pCR and outcome prediction of ESCCs through a multicenter analysis for a Chinese population.

Methods

Differentially expressed lncRNAs (DELs) between pCRs and less than pCR (

SUBMITTER: Zhang C 

PROVIDER: S-EPMC7448795 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature