Potential of the natural products against leishmaniasis in Old World - a review of in-vitro studies.

ABSTRACT: Leishmaniasis is a vector-borne disease among the 10 most Neglected Tropical Diseases with diverse clinical manifestations caused by protozoan parasites of the Leishmania genus. Around 80% of leishmaniasis cases are found in the Old World affecting populations mainly in low and middle-income countries. Its control relies mostly on chemotherapy which still presents many drawbacks. Natural products may offer an inexhaustible source of chemical diversity with therapeutic potential. Despite the lack of knowledge on traditional products with activity against Leishmania parasites, many reports describe the search for natural extracts and compounds with antileishmanial properties against promastigote and amastigote parasite forms. This review summarizes the research of 74 publicatio

SUBMITTER: Cortes S 

PROVIDER: S-EPMC7448914 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature