The association between FTO genotype with macronutrients and calorie intake in overweight adults.

ABSTRACT:

Background

Dietary macronutrients may indirectly affect body weight through their interactions with the fat mass and obesity associated (FTO) gene. This study aimed to investigate the association between FTO gene rs9939609 polymorphism with macronutrients intake in overweight adults.

Methods

This study was carried out on 196 overweight adults of Shiraz, Iran. Dietary intake was assessed using a validated 168-item semi-quantitative food frequency questionnaire (FFQ). The FTO gene was genotyped for rs9939609 polymorphism. The association between dietary macronutrients and the FTO genotype were assessed using linear regression after adjustments for sex, age, physical activity, and the serum levels of triglycerides, fasting blood sugar (FBS), and low density lipoprotein (LDL).

SUBMITTER: Mehrdad M 

PROVIDER: S-EPMC7449073 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature