Living kidney donation in individuals with hepatitis C and HIV infection: rationale and emerging evidence.

ABSTRACT:

Purpose of review

HIV-infected (HIV+) and hepatitis C virus-infected (HCV+) individuals with end-stage renal disease (ESRD) have decreased access to kidney transplantation. With new opportunities provided by the HIV Organ Policy Equity (HOPE) Act and direct-acting antivirals (DAAs) for HCV, we explore the potential risks and benefits of living donor kidney transplantation from HIV+ or HCV+ donors, from the perspective of both donor health and recipient outcomes.

Recent findings

The HOPE Act permits organ donation from both deceased and living HIV+ persons to HIV+ recipients; however, there is only clinical experience with HIV+ deceased donors to date. Empirical evidence demonstrates a low but acceptable risk of ESRD in potential HIV+ living donors without comorbidities who h

SUBMITTER: Liyanage L 

PROVIDER: S-EPMC7449146 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature