Effect of hydroxychloroquine with or without azithromycin on the mortality of coronavirus disease 2019 (COVID-19) patients: a systematic review and meta-analysis.

ABSTRACT:

Background

Hydroxychloroquine or chloroquine with or without azithromycin have been widely promoted to treat coronavirus disease 2019 (COVID-19) following early in vitro antiviral effects against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

Objective

The aim of this systematic review and meta-analysis was to assess whether chloroquine or hydroxychloroquine with or without azithromycin decreased COVID-19 mortality compared with the standard of care.

Data sources

PubMed, Web of Science, Embase Cochrane Library, Google Scholar and MedRxiv were searched up to 25 July 2020.

Study eligibility criteria

We included published and unpublished studies comparing the mortality rate between patients treated with chloroquine or hydroxychloroquine with or with

SUBMITTER: Fiolet T 

PROVIDER: S-EPMC7449662 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature