Ontology highlight
ABSTRACT:
SUBMITTER: Baumel WT
PROVIDER: S-EPMC7449670 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Baumel W Thomas WT Constantino John N JN
Journal of the American Academy of Child and Adolescent Psychiatry 20200901 9
Although biological processes have been directly targeted to substantial advantage in effective treatments for major depression, the evidence base for addressing potential "existential" contributions to depressive syndromes has lagged behind that related to other tractable mediators of the condition, such as cognitive bias, nonadaptive learned behavior, and variation in monoamine neurotransmission. Whether the experience of existential conflict is a cause or an effect of these phenomena is incom ...[more]