Electrophoretic Separations on Parafilm-Paper-Based Analytical Devices.

ABSTRACT: Microfluidic paper-based analytical devices (mPADs) have gained significant attention in recent years for applications ranging from clinical diagnostics to environmental testing. However, separation on mPADs remain challenging to implement, particularly in complex samples. This has revived interest in revisiting paper chromatography and paper electrophoresis in mPADs to address these needs. Here, laminated Parafilm-paper (l-paper) is applied to fabricate electrophoretic devices. This approach yields a free-standing channel, leading to improved peak resolution relative to previous electrophoretic separations in traditional wax-printed mPADs. Major factors influencing the separation, including Joule heating, electroosmotic flow, and electrophoretic mobility, were investigated. As a result of

SUBMITTER: Mettakoonpitak J 

PROVIDER: S-EPMC7450514 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature