Coumarin-Calix[4]arene Conjugate-Anchored SiO₂ Nanoparticles as an Ultrasensor Material for Fe³⁺ to Work in Water, in Serum, and in Biological Cells.

ABSTRACT: A coumarin-appended calixarene derivative ( CouC4A ) and a hybrid material generated by covalently linking this onto a silica surface ( CouC4A@SiO ₂ ) were synthesized and were characterized by various analytical, spectroscopy, and microscopy methods. Both these materials are capable of sensing Fe³⁺ with greater sensitivity and selectivity. The sensitivity is enhanced by 30,000 fold on going from a simple solution phase to the silica surface with the limit of Fe³⁺ detection being 1.75 ± 0.4 pM when CouC4A@SiO ₂ is used, and the sensing is partially reversible with phosphates, while it is completely reversible with adenosine 5'-triphosphate (ATP). While the calix precursor, Cou

SUBMITTER: Uttam B 

PROVIDER: S-EPMC7450711 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature