Prospective evaluation of ⁶⁸ Ga-DOTATATE PET/CT in limited disease neuroendocrine tumours and/or elevated serum neuroendocrine biomarkers.

ABSTRACT:

Context

The ⁶⁸ Ga-labelled somatostatin analogues (⁶⁸ Ga-DOTA-SSAs) is becoming popular as an important diagnostic tool in neuroendocrine tumours as evidenced by a growing number of reports detailing institutional experience with various DOTA peptides. However, only few prospective studies have compared ⁶⁸ Ga-DOTA-SSAs and somatostatin receptor scintigraphy (SRS) in gastroenteropancreatic neuroendocrine tumours (GEP-NETs) and pulmonary neuroendocrine tumours.

Objective

The aim of our prospective study was to perform head-to-head comparison between ⁶⁸  Ga-DOTATATE PET/CT and standard imaging work-up (SI) that included multiphasic CT, liver MRI and SRS using single photon emission computed tomography.

Design

In this prospectiv

SUBMITTER: Gabriel S 

PROVIDER: S-EPMC7450718 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature