Prevalence, concordance and associations of chronic kidney disease by five estimators in South Africa.

ABSTRACT:

Background

To determine the prevalence, distribution, concordance and associations of chronic kidney disease (CKD) determined by five glomerular filtration rate (GFR) formulae in urban black residents of Cape Town.

Methods

Data collection in this cross-sectional study included interviews, clinical measurements and biochemical analyses, including serum creatinine and cystatin C levels. GFR was based on the CKD Epidemiology Collaboration (CKD-EPI) equations (CKD-EPI creatinine (CKD-EPIcr), CKD-EPI cystatin C (CKD-EPIcys), CKD-EPI creatinine-cystatins (CKD-EPIcr-cys)), Modification of Diet in Renal Disease (MDRD) and Cockcroft-Gault formula (CGF). GFR < 60 mL/min/1.73 m² defined CKD.

Results

Among 392 men and 700 women, mean GFR, was between 114.0 (CKD-EPIcr)

SUBMITTER: Peer N 

PROVIDER: S-EPMC7451105 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature