Intrapericardial recombinant tissue plasminogen activator in purulent pericarditis- case series.

ABSTRACT:

Background

Pericardial constriction is one of the complications of purulent pericarditis (PP). Most difficult to treat, which may develop both in early and in the late period of the disease, resulting in a very poor prognosis.

Case presentation

We present case series of 4 patients with purulent pericarditis, in whom direct intrapericardial administration of recombinant tissue plasminogen activator (r-tPA) was used. Management of PP requires a combined surgical and medical approach. The most important is complete drainage of the effusion by subxiphoid pericardiotomy connected with complementary use of broad-spectrum antibiotics. Despite the use of broad- spectrum antibiotics, in some patients a large volume of daily drainage is still present. Constrictive pericarditis as a co

SUBMITTER: Dybowska M 

PROVIDER: S-EPMC7451238 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature