Is there an association between subjective sleep quality and daily delirium occurrence in critically ill adults? A post hoc analysis of a randomised controlled trial.

ABSTRACT:

Objectives

Whether and how delirium and sleep quality in the intensive care unit (ICU) are linked remains unclear. A recent randomised trial reported nocturnal low-dose dexmedetomidine (DEX) significantly reduces incident ICU delirium. Leeds Sleep Evaluation Questionnaire (LSEQ) scores were similar between intervention (DEX; n=50) and control (placebo (PLA); n=50) groups. We measured the association between morning LSEQ and delirium occurrence in the prior 24 hours (retrospective analysis) and the association between morning LSEQ and delirium occurrence in the following 24 hours (predictive analysis).

Design

Post hoc analysis of randomised controlled trial data.

Participants

Adult ICU patients (n=100) underwent delirium screening twice a day using the Intensive Care D

SUBMITTER: Duprey MS 

PROVIDER: S-EPMC7451265 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature