Evaluation of whole-body MRI with diffusion-weighted sequences in the staging of pediatric cancer patients.

ABSTRACT:

Background

The purpose of this study was to determine whether whole-body MRI (WBMRI) with diffusion-weighted sequences, which is free of ionizing radiation, can perform as well as traditional methods when used alone for staging or follow-up of pediatric cancer patients.

Methods

After obtaining approval from our institutional research ethics committee and appropriate informed consent, we performed 34 examinations in 32 pediatric patients. The examinations were anonymized and analyzed by two radiologists with at least 10 years' experience.

Results

The sensitivity and specificity findings, respectively, were as follows: 100% and 100% for primary tumor; 100% and 86% for bone metastasis; 33% and 100% for lung metastasis; 85% and 100% for lymph node metastasis; and 100% and

SUBMITTER: de Oliveira AD 

PROVIDER: S-EPMC7451574 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature