Synergistic effects of immunoregulation and osteoinduction of ds-block elements on titanium surface.
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ABSTRACT: Ds-block elements have been gaining increasing attention in the field of biomaterials modification, owing to their excellent biological properties, such as antibiosis, osteogenesis, etc. However, their function mechanisms are not well understood and conflicting conclusions were drawn by previous studies on this issue, which are mainly resulted from the inconsistent experimental conditions. In this work, three most widely used ds-block elements, copper, zinc, and silver were introduced on titanium substrate by plasma immersion ion implantation method to investigate the rule of ds-block elements in the immune responses. Results showed that the implanted samples could decrease the inflammatory responses compared with Ti sample. The trend of anti-inflammatory effects of macrophages on samples
SUBMITTER: Chen L
PROVIDER: S-EPMC7452063 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
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