Effects of Narrowband Light on Choroidal Thickness and the Pupil.

ABSTRACT:

Purpose

To determine the effects of narrowband light exposure on choroidal thickness and the pupil response in humans.

Methods

Twenty subjects, ages 21 to 43 years, underwent 1 hour of exposure to broadband, short wavelength "blue," or long wavelength "red" light, or darkness. Choroidal thickness, imaged with spectral domain optical coherence tomography, axial length, determined from biometry, and rod/cone- and intrinsically photosensitive retinal ganglion cell-driven pupil responses were measured before and after exposure. Pupil stimuli were six 1 second alternating red (651 nm) and blue (456 nm) stimuli, 60 seconds apart. Pupil metrics included maximum constriction and the 6 second post-illumination pupil response (PIPR).

Results

Compared with before exposure, the c

SUBMITTER: Lou L 

PROVIDER: S-EPMC7452857 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature