Distinct topographic-anatomical patterns in primary and secondary brain tumors and their therapeutic potential.

ABSTRACT:

Purpose

Understanding the topographic-anatomical patterns of brain tumors has the potential to improve our pathophysiological understanding and may allow for anatomical tailoring of surgery and radiotherapy. This study analyzed topographic-anatomical patterns underlying neuroepithelial tumors, primary CNS lymphoma and metastases.

Methods

Any histologically confirmed supra- or infratentorial parenchymal neoplasia of one institution over a 4-year period was included. Using high-resolution magnetic resonance imaging data, a detailed analysis of the topographic-anatomical tumor features was performed. Differences between neuroepithelial tumors, primary central nervous system lymphoma (PCNSL) and metastases were assessed using pairwise comparisons adjusted for multiple testing, u

SUBMITTER: Akeret K 

PROVIDER: S-EPMC7452943 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature