Non-operative management for oral cavity carcinoma: Definitive radiation therapy as a potential alternative treatment approach.

ABSTRACT:

Purpose

To determine the outcomes of oral cavity squamous cell cancer (OSCC) patients treated with non-surgical approach i.e. definitive intensity-modulated radiation therapy (IMRT).

Methods

All OSCC patients treated radically with IMRT (without primary surgery) between 2005-2014 were reviewed in a prospectively collected database. OSCC patients treated with definitive RT received concurrent chemotherapy except for early stage patients or those who declined or were unfit for chemotherapy. The 5-year local, and regional, distant control rates, disease-free, overall, and cancer-specific survival, and late toxicity were analyzed.

Results

Among 1316 OSCC patients treated with curative-intent; 108 patients (8%) received non-operative management due to: medical inoperabilit

SUBMITTER: Hosni A 

PROVIDER: S-EPMC7453211 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature