Ontology highlight
ABSTRACT: Objectives
We investigated whether self-reported disability was associated with mortality in adults in rural Malawi.Setting
Karonga Health and Demographic Surveillance Site (HDSS), Northern Malawi.Participants
All adults aged 18 and over residing in the HDSS were eligible to participate. During annual censuses in 2014 and 2015, participants were asked if they experienced difficulty in any of six functional domains and were classified as having disabilities if they reported 'a lot of difficulty' or 'can't do at all' in any domain. Mortality data were collected until 31 December 2017. 16 748 participants (10 153 women and 6595 men) were followed up for a median of 29 months.Primary and secondary outcome measures
We used Poisson regression to examine the relationship between disability and all-cause mortality adjusting for confounders. We assessed whether this relationship altered in the context of obesity, hypertension, diabetes or HIV. We also evaluated whether mortality from non-communicable diseases (NCD) was higher among people who had reported disability, as determined by verbal autopsy.Results
At baseline, 7.6% reported a disability and the overall adult mortality rate was 9.1/1000 person-years. Adults reporting disability had an all-cause mortality rate 2.70 times higher than those without, and mortality rate from NCDs 2.33 times higher than those without.Conclusions
Self-reported disability predicts mortality at all adult ages in rural Malawi. Interventions to improve access to healthcare and other services are needed.
SUBMITTER: Prynn JE
PROVIDER: S-EPMC7454196 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Prynn Josephine E JE Dube Albert A Mkandawire Joseph J Koole Olivier O Geis Steffen S Mwaiyeghele Elenaus E Mwiba Oddie O Price Alison J AJ Kachiwanda Lackson L Nyirenda Moffat M Kuper Hannah H Crampin Amelia C AC
BMJ open 20200827 8
<h4>Objectives</h4>We investigated whether self-reported disability was associated with mortality in adults in rural Malawi.<h4>Setting</h4>Karonga Health and Demographic Surveillance Site (HDSS), Northern Malawi.<h4>Participants</h4>All adults aged 18 and over residing in the HDSS were eligible to participate. During annual censuses in 2014 and 2015, participants were asked if they experienced difficulty in any of six functional domains and were classified as having disabilities if they reporte ...[more]