Dataset Information

Antibiotic use in patients with COVID-19: a 'snapshot' Infectious Diseases International Research Initiative (ID-IRI) survey.

ABSTRACT:

Background

Antibiotics may be indicated in patients with COVID-19 due to suspected or confirmed bacterial superinfection.

Objectives

To investigate antibiotic prescribing practices in patients with COVID-19.

Methods

We performed an international web-based survey and investigated the pattern of antibiotic use as reported by physicians involved in treatment of COVID-19. SPSS Statistics version 25 was used for data analysis.

Results

The survey was completed by 166 participants from 23 countries and 82 different hospitals. Local guidelines for antibiotic use in COVID-19 patients were reported by 61.8% (n = 102) of participants and for 82.9% (n = 136) they did not differ from local community-acquired pneumonia guidelines. Clinical presentation was recognized as the most important reason for the start of antibiotics (mean score = 4.07 and SD = 1.095 on grading scale from 1 to 5). When antibiotics were started, most respondents rated as the highest the need for coverage of atypical pathogens (mean score = 2.8 and SD = 0.99), followed by Staphylococcus aureus (mean score = 2.67 and SD = 1.05 on bi-modal scale, with values 1 and 2 for disagreement and values 3 and 4 for agreement). In the patients on the ward, 29.1% of respondents chose not to prescribe any antibiotic. Combination of β-lactams and macrolides or fluoroquinolones was reported by 52.4% (n = 87) of respondents. In patients in the ICU, piperacillin/tazobactam was the most commonly prescribed antibiotic. The mean reported duration of antibiotic treatment was 7.12 (SD = 2.44) days.

Conclusions

The study revealed widespread broad-spectrum antibiotic use in patients with COVID-19. Implementation of antimicrobial stewardship principles is warranted to mitigate the negative consequences of antibiotic therapy.

SUBMITTER: Beovic B

PROVIDER: S-EPMC7454563 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature

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Publications

Antibiotic use in patients with COVID-19: a 'snapshot' Infectious Diseases International Research Initiative (ID-IRI) survey.

Beović Bojana B Doušak May M Ferreira-Coimbra João J Nadrah Kristina K Rubulotta Francesca F Belliato Mirko M Berger-Estilita Joana J Ayoade Folusakin F Rello Jordi J Erdem Hakan H

The Journal of antimicrobial chemotherapy 20201101 11

<h4>Background</h4>Antibiotics may be indicated in patients with COVID-19 due to suspected or confirmed bacterial superinfection.<h4>Objectives</h4>To investigate antibiotic prescribing practices in patients with COVID-19.<h4>Methods</h4>We performed an international web-based survey and investigated the pattern of antibiotic use as reported by physicians involved in treatment of COVID-19. SPSS Statistics version 25 was used for data analysis.<h4>Results</h4>The survey was completed by 166 parti ...[more]

PMID: 32766706

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Dataset Information

Antibiotic use in patients with COVID-19: a 'snapshot' Infectious Diseases International Research Initiative (ID-IRI) survey.

Background

Objectives

Methods

Results

Conclusions

Publications

Antibiotic use in patients with COVID-19: a 'snapshot' Infectious Diseases International Research Initiative (ID-IRI) survey.

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