Incidence of intussusception before and after the introduction of rotavirus vaccine in Korea.

ABSTRACT:

Background

Recent studies have reported that after the introduction of rotavirus vaccine the incidence of intussusception did not change among infants, or slightly increased at the age immediately after the first dose. The rotavirus vaccines were introduced in Korea for private market use in 2007-2008. We investigated the incidence of intussusception before (2002-2006) and after (2009-2015) the vaccine introduction in Korea.

Methods

We conducted an interrupted time series study that used data from the Korean National Health Insurance database to identify infants (<12 months of age) who were diagnosed with intussusception and underwent non-invasive or invasive reduction from 2002 to 2015. According to the recommended ages for immunization, the annual intussusception incidence

SUBMITTER: Cho HK 

PROVIDER: S-EPMC7454960 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature