Brain fog and non-coeliac gluten sensitivity: Proof of concept brain MRI pilot study.

ABSTRACT:

Aims

Non-Coeliac Gluten Sensitivity (NCGS) is poorly understood, particularly in terms of its neurological outcomes. We initially conducted a prospective postal survey to investigate its neurological presentation and symptom course. Results from this then motivated a follow-up pilot study utilising brain MRI to characterise potential diagnostic biomarkers for future research.

Methods

Patients with NCGS were recruited from a specialist centre and completed a prospective postal questionnaire (N = 125). This summarised symptoms experienced, their severity and their course. Onset time was compared by Chi-squared analysis to data from the same centre concerning coeliac disease patients (N = 224). Five respondents on a strict gluten-free diet who self-reported brain fog then atten

SUBMITTER: Croall ID 

PROVIDER: S-EPMC7454984 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature