Spectrum of cerebral arteriopathies in children with arterial ischemic stroke.

ABSTRACT:

Objective

To determine that children with arterial ischemic stroke (AIS) due to an identifiable arteriopathy are distinct from those without arteriopathy and that each arteriopathy subtype has unique and recognizable clinical features.

Methods

We report a large, observational, multicenter cohort of children with AIS, age 1 month to 18 years, enrolled in the International Pediatric Stroke Study from 2003 to 2014. Clinical and demographic differences were compared by use of the Fisher exact test, with linear step-up permutation min-p adjustment for multiple comparisons. Exploratory analyses were conducted to evaluate differences between cases of AIS with and without arteriopathy and between arteriopathy subtypes.

Results

Of 2,127 children with AIS, 725 (34%) had

SUBMITTER: Rafay MF 

PROVIDER: S-EPMC7455362 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature