Assessing vitamin D related genetic variants, status, and influence factors in pregnant women in Eastern and Central China.

ABSTRACT: Vitamin D deficiency has recently become a global public health problem. However, it is still unclear if gene polymorphisms in the vitamin D pathway influence vitamin D levels among pregnant women in Eastern and Central China. The objective of this study was to assess factors influencing vitamin D levels in pregnant women. A total of 326 participants in Shandong and Henan provinces in China were enrolled from August 2017 to April 2019. Serum 25(OH)D levels and single nucleotide polymorphisms (SNPs) in the vitamin D pathway were measured using the blood samples collected in the first trimester, second trimester, and third trimester. Data on demographics, lifestyle, and health behavior were collected using a questionnaire. Statistical analyses were performed using the R software. The prevale

SUBMITTER: Qiu X 

PROVIDER: S-EPMC7455978 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature