Genetic profile of African swine fever virus responsible for the 2019 outbreak in northern Malawi.

ABSTRACT:

Background

African swine fever (ASF) is an infectious transboundary animal disease which causes high mortality, approaching 100% in domestic pigs and it is currently considered as the most serious constraint to domestic pig industry and food security globally. Despite regular ASF outbreaks within Malawi, few studies have genetically characterized the causative ASF virus (ASFV). This study aimed at genetic characterization of ASFV responsible for the 2019 outbreak in northern Malawi. The disease confirmation was done by polymerase chain reaction (PCR) followed by molecular characterization of the causative ASFV by partial genome sequencing and phylogenetic reconstruction of the B646L (p72) gene, nucleotide alignment of the intergenic region (IGR) between I73R and I329L genes and tra

SUBMITTER: Hakizimana JN 

PROVIDER: S-EPMC7455991 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature