Parental occupational exposure to pesticides and risk of childhood cancer in Switzerland: a census-based cohort study.

ABSTRACT:

Background

Pesticide exposure is a suspected risk factor for childhood cancer. We investigated the risk of developing childhood cancer in relation to parental occupational exposure to pesticides in Switzerland for the period 1990-2015.

Methods

From a nationwide census-based cohort study in Switzerland, we included children aged < 16 years at national censuses of 1990 and 2000 and followed them until 2015. We extracted parental occupations reported at the census closest to the birth year of the child and estimated exposure to pesticides using a job exposure matrix. Cox proportional hazards models, adjusted for potential confounders, were fitted for the following outcomes: any cancer, leukaemia, central nervous system tumours (CNST), lymphoma, non-CNS solid tumours.

Results

SUBMITTER: Coste A 

PROVIDER: S-EPMC7456012 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature