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The treatment strategy of R0 resection in colorectal cancer with synchronous para-aortic lymph node metastasis.


ABSTRACT:

Background

Synchronous metastatic para-aortic lymph node (mPALN) dissectionin colorectal cancer has relatively good oncological outcomes, though many patients develop recurrence. Universal prognostic factor remain unclear and no definitive perioperative chemotherapy is available, making the treatment of mPALN controversial. In the present study, we aimed to establish a treatment strategy for synchronous mPALN.

Methods

This retrospective study involved 20 patients with pathological mPALN below the renal vein who underwent R0 resection. Long-term outcomes, recurrence type, and prognostic factors for survival were investigated.

Results

The 5-year overall survival and recurrence-free survival rates were 39% and 25%, respectively. Seventeen patients (85%) developed recurre

SUBMITTER: Ushigome H 

PROVIDER: S-EPMC7456015 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature