2000-year-old pathogen genomes reconstructed from metagenomic analysis of Egyptian mummified individuals.

ABSTRACT:

Background

Recent advances in sequencing have facilitated large-scale analyses of the metagenomic composition of different samples, including the environmental microbiome of air, water, and soil, as well as the microbiome of living humans and other animals. Analyses of the microbiome of ancient human samples may provide insights into human health and disease, as well as pathogen evolution, but the field is still in its very early stages and considered highly challenging.

Results

The metagenomic and pathogen content of Egyptian mummified individuals from different time periods was investigated via genetic analysis of the microbial composition of various tissues. The analysis of the dental calculus' microbiome identified Red Complex bacteria, which are correlated with periodon

SUBMITTER: Neukamm J 

PROVIDER: S-EPMC7456089 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature