The whale shark genome reveals how genomic and physiological properties scale with body size.

ABSTRACT: The endangered whale shark (Rhincodon typus) is the largest fish on Earth and a long-lived member of the ancient Elasmobranchii clade. To characterize the relationship between genome features and biological traits, we sequenced and assembled the genome of the whale shark and compared its genomic and physiological features to those of 83 animals and yeast. We examined the scaling relationships between body size, temperature, metabolic rates, and genomic features and found both general correlations across the animal kingdom and features specific to the whale shark genome. Among animals, increased lifespan is positively correlated to body size and metabolic rate. Several genomic traits also significantly correlated with body size, including intron and gene length. Our large-scale compa

SUBMITTER: Weber JA 

PROVIDER: S-EPMC7456109 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature