An observational report of universal GeneXpert testing of inpatients with diagnosed or presumptive TB in the Philippines.

ABSTRACT:

Background

The Philippines is a high TB and multidrug-resistant TB burden country. Although the scale-up of GeneXpert testing is occurring, the benefits of universal Xpert-Mycobacterium tuberculosis/ rifampicin (MTB/RIF) testing in inpatients have not been documented.

Methods

Routine GeneXpert testing irrespective of priority criteria for testing was conducted within a prospective cohort of all adults with known or presumptive TB admitted to a tertiary infectious diseases hospital in Manila. Study-specific TB diagnosis was decided upon bacteriological results, chest x-ray assessment, if already on anti-TB treatment (ATT) at admission and a cough duration of ≥2 wk.

Results

Of submitted sputum samples, 87.1% (277/318) had valid acid-fast bacilli (AFB) microscopy and Xpe

SUBMITTER: Thi AM 

PROVIDER: S-EPMC7456596 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature