Total, free, and complexed prostate-specific antigen levels among US men, 2007-2010.

ABSTRACT:

Background

Screening for prostate cancer using prostate-specific antigen (PSA) is common. Prostate cancer has been associated with higher total PSA (tPSA), lower free PSA (fPSA), lower percent free PSA (%fPSA), and higher complexed PSA (cPSA).

Methods

Total, free and complexed PSAs were performed on 3251 men ≥40years in the 2007-2010 National Health and Nutrition Examination Survey. Distributions of the PSA tests were examined by age, race and ethnicity, and body mass index (BMI) groups. Percentages of men at PSA thresholds were examined.

Results

Total PSA geometric mean was 0.96μg/l among men aged ≥40years and increased from 0.74μg/l for men 40-49years, to 1.82μg/l for men 80years and older. Non-Hispanic Whites had lower age-adjusted mean tPSA (1.03μg/l) and cPSA (0.

SUBMITTER: Lacher DA 

PROVIDER: S-EPMC7456738 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature