Modeling of Xerostomia After Radiotherapy for Head and Neck Cancer: A Registry Study.

ABSTRACT:

Aim

Data from a local quality registry are used to model the risk of late xerostomia after radiotherapy for head and neck cancer (HNC), based on dosimetric- and clinical variables. Strengths and weaknesses of using quality registry data are explored.

Methods

HNC patients treated with radiotherapy at the Karolinska University hospital are entered into a quality registry at routine follow up, recording morbidity according to a modified RTOG/LENT-SOMA scale. Other recorded parameters are performance status, age, gender, tumor location, tumor stage, smoking status, chemotherapy and radiotherapy data, including prescribed dose and organ-at-risk (OAR) dose. Most patients are entered at several time points, but at variable times after treatment. Xerostomia was modeled based on foll

SUBMITTER: Onjukka E 

PROVIDER: S-EPMC7456883 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature