Zebrafish Circadian Clock Entrainment and the Importance of Broad Spectral Light Sensitivity.

ABSTRACT: One of the key defining features of an endogenous circadian clock is that it can be entrained or set to local time. Though a number of cues can perform this role, light is the predominant environmental signal that acts to entrain circadian pacemakers in most species. For the past 20 years, a great deal of work has been performed on the light input pathway in mammals and the role of intrinsically photosensitive retinal ganglion cells (ipRGCs)/melanopsin in detecting and sending light information to the suprachiasmatic nucleus (SCN). In teleost fishes, reptiles and birds, the biology of light sensitivity is more complicated as cells and tissues can be directly light responsive. Non-visual light signalling was described many years ago in the context of seasonal, photoperiodic responses in bir

SUBMITTER: Steindal IAF 

PROVIDER: S-EPMC7456917 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature