Analysis of the brain transcriptome in lines of laying hens divergently selected for feather pecking.

ABSTRACT:

Background

Feather pecking (FP) in laying hens reduces animal welfare and leads to economic losses for the layer industry. FP is considered a heritable condition that is influenced by dysregulation of neurotransmitter homeostasis, the gut microbiome, and the immune system. To identify genes and biological pathways responsible for FP behavior we compared the brain transcriptomes of 48 hens divergently selected for FP. In addition, we tested if high feather peckers (HFP) and low feather peckers (LFP) respond differently to light since light has been shown to trigger FP behavior.

Results

Of approximately 48 million reads/sample an average of 98.4% were mapped to the chicken genome (GRCg6a). We found 13,070 expressed genes in the analyzed brains of which 423 showed differential

SUBMITTER: Falker-Gieske C 

PROVIDER: S-EPMC7457272 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature