Honeybee products and edible insect powders improve locomotive and learning abilities of Ubiquilin-knockdown Drosophila.

ABSTRACT:

Background

Mutations in the human Ubiquilin 2 gene are associated with neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) with or without frontotemporal dementia (FTD), the fatal neurodegenerative disease that progressively affected neuronal cells in both brain and spinal cord. There is currently no effective therapy for these diseases. Over the last decade, researchers have focused on the potential use of natural products especially in neurodegenerative studies. Insect products have been used as traditional medicines, however, scientific information is still lacking. Fruit fly is recently used as a model organism to investigate degenerative diseases related to the nervous system because it has a short life span and produces a large number of offspring.

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SUBMITTER: Phokasem P 

PROVIDER: S-EPMC7457359 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature