Infectious and inflammatory disorders might increase the risk of developing idiopathic intracranial hypertension - a national case-control study.

ABSTRACT:

Objective

To investigate whether conditions causing inflammatory activation are associated with increased risk of idiopathic intracranial hypertension.

Methods

All newly diagnosed idiopathic intracranial hypertension patients (cases) in Sweden between 2000-2016 were identified using pre-determined algorithms (n = 902) and matched with five controls from the general population and five individuals with an obesity diagnosis (n = 4510) for age, sex, region, and vital status. National health registers provided information on infections, inflammatory disorders and dispensed medications. Conditional logistic regression was used to estimate odds ratios and 95% confidence intervals.

Results

Compared to general population controls, the cases had fourfold increased odds of havi

SUBMITTER: Sundholm A 

PROVIDER: S-EPMC7457460 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature