Body-mass index and long-term risk of sepsis-related mortality: a population-based cohort study of 0.5 million Chinese adults.

ABSTRACT:

Background

Sepsis represents a major worldwide healthcare burden. However, how body-mass index (BMI) is related to the long-term risk of sepsis-related mortality in low- and middle-income countries remains uncertain.

Methods

We examined the associations of sepsis-related mortality with both baseline BMI and waist circumference (WC) using data from China Kadoorie Biobank, a prospective cohort recruited during 2004-2008 and followed up to December 2016. After excluding participants with chronic obstructive pulmonary disease, tuberculosis, cancer, heart disease, and stroke, and omitting the first 3 years of follow-up, 440,763 participants remained for analysis.

Results

During a median follow-up of 10.0 years, 1957 sepsis-related deaths (3,134,870 person-years) were inclu

SUBMITTER: Weng L 

PROVIDER: S-EPMC7457784 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature