Extracellular Vesicles - Advanced Nanocarriers in Cancer Therapy: Progress and Achievements.

ABSTRACT: Extracellular vesicles (EVs) are a class of cell-derived, lipid bilayer membrane composed vesicles, and some of them such as exosomes and ectosomes have been proven, playing remarkable roles in transmitting intercellular information, and being involved in each property of cell physiological activities. Nowadays, EVs are considered as potential nanocarriers which could partially resolve the problems of current chemotherapy because of their distinctive advantages. As endogenous membrane encompassed vesicles with nanosize, EVs are able to pass through the natural barriers with prolonged circulation time in vivo and have intrinsic cell targeting properties, they are less toxic, and less immunogenic. Recently, studies focusing on EV-based drug delivery system for cancer therapy have exploded dr

SUBMITTER: Huyan T 

PROVIDER: S-EPMC7457829 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature