Risk factors for and prediction of post-intubation hypotension in critically ill adults: A multicenter prospective cohort study.

ABSTRACT:

Objective

Hypotension following endotracheal intubation in the ICU is associated with poor outcomes. There is no formal prediction tool to help estimate the onset of this hemodynamic compromise. Our objective was to derive and validate a prediction model for immediate hypotension following endotracheal intubation.

Methods

A multicenter, prospective, cohort study enrolling 934 adults who underwent endotracheal intubation across 16 medical/surgical ICUs in the United States from July 2015-January 2017 was conducted to derive and validate a prediction model for immediate hypotension following endotracheal intubation. We defined hypotension as: 1) mean arterial pressure <65 mmHg; 2) systolic blood pressure <80 mmHg and/or decrease in systolic blood pressure of 40% from baseline;

SUBMITTER: Smischney NJ 

PROVIDER: S-EPMC7458292 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature