Gene expression profiles of the small intestine of village chickens from an Ascaridia galli infested environment.

ABSTRACT: Nematodes of the genus Ascaridia are known to infect many species of birds and result in fatal diseases. A. galli damages the intestinal mucosa of chickens leading to blood loss, secondary infection and occasionally the obstruction of small intestines due to high worm burden. This study investigated the gene expression profiles in chickens from two different provinces of South Africa naturally exposed to A. galli infestations and tested either positive or negative for the parasite. The study further investigated gene expression profiles of the A. galli infected duodenum, jejunum and ileum tissues of the small intestines. The A. galli positive intestines displayed hypertrophy of the intestinal villi with accumulation of inflammatory cells and necrosis of t

SUBMITTER: Malatji DP 

PROVIDER: S-EPMC7458390 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature