Glycemic index, glycemic load, and risk of coronary heart disease: a pan-European cohort study.

ABSTRACT:

Background

High carbohydrate intake raises blood triglycerides, glucose, and insulin; reduces HDLs; and may increase risk of coronary heart disease (CHD). Epidemiological studies indicate that high dietary glycemic index (GI) and glycemic load (GL) are associated with increased CHD risk.

Objectives

The aim of this study was to determine whether dietary GI, GL, and available carbohydrates are associated with CHD risk in both sexes.

Methods

This large prospective study-the European Prospective Investigation into Cancer and Nutrition-consisted of 338,325 participants who completed a dietary questionnaire. HRs with 95% CIs for a CHD event, in relation to intake of GI, GL, and carbohydrates, were estimated using covariate-adjusted Cox proportional hazard models.

Results

SUBMITTER: Sieri S 

PROVIDER: S-EPMC7458777 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature