Social Economic Costs, Health-Related Quality of Life and Disability in Patients with Cri Du Chat Syndrome.

ABSTRACT: Background: Cri du Chat syndrome (CdC) is a rare disease caused by the deletion on the short arm of the chromosome 5, with an incidence of 1:15,000 to 1:50,000 live-born infants. No study at international level has assessed the costs, Quality of Life (QoL) and Disability through standardized quantitative tools. The aim is to estimate economic costs related to CdC from a societal perspective, to assess the QoL and Disability in patients with CdC along with their caregivers in Italy. Methods: A cross-sectional study of patients with Cri du Chat in Italy was carried out. A cost of illness approach from a societal perspective was used to estimate cost, and a micro-costing method was adopted. The QoL was measured with EuroQol 5-domain (EQ-5D) questionnaire and Disability by using

SUBMITTER: Kodra Y 

PROVIDER: S-EPMC7459640 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature