Antibiotic Resistance of Legionella pneumophila in Clinical and Water Isolates-A Systematic Review.

ABSTRACT: The current systematic review investigates the antibiotic susceptibility pattern of Legionella pneumophila isolates from the 1980s to the present day, deriving data from clinical and/or water samples from studies carried out all over the world. Eighty-nine papers meeting the inclusion criteria, i.e., "Legionella pneumophila" and "resistance to antibiotics", were evaluated according to pre-defined validity criteria. Sixty articles referred to clinical isolates, and 18 articles reported water-related L. pneumophila isolates, while 11 articles included both clinical and water isolates. Several methods have been proposed as suitable for the determination of MICs, such as the E-test, broth and agar dilution, and disk diffusion methods, in vivo and in vitro, using various media. The E-test metho

SUBMITTER: Pappa O 

PROVIDER: S-EPMC7459901 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature