Influence of Sulfonamide Contamination Derived from Veterinary Antibiotics on Plant Growth and Development.

ABSTRACT: Veterinary antibiotics such as sulfonamides are widely used to increase feed efficiency and to protect against disease in livestock production. The sulfonamide antimicrobial mechanism involves the blocking of folate biosynthesis by inhibiting bacterial dihydropteroate synthase (DHPS) activity competitively. Interestingly, most treatment antibiotics can be released into the environment via manure and result in significant diffuse pollution in the environment. However, the physiological effects of sulfonamide during plant growth and development remain elusive because the plant response is dependent on folate biosynthesis and the concentration of antibiotics. Here, we present a chemical interaction docking model between Napa cabbage (Brassica campestris) DHPS and sulfamethoxazole and sulfamet

SUBMITTER: Cheong MS 

PROVIDER: S-EPMC7460019 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature