Assessing Global Frailty Scores: Development of a Global Burden of Disease-Frailty Index (GBD-FI).

ABSTRACT: Frailty is an independent age-associated predictor of morbidity and mortality. Despite this, many countries lack population estimates with large heterogeneity between studies. No population-based standardised metric for frailty is available. We applied the deficit accumulation model of frailty to create a frailty index (FI) using population-level estimates from the Global Burden of Disease (GBD) 2017 study across 195 countries to create a novel GBD frailty index (GBD-FI). Standard FI criteria were applied to all GBD categories to select GBD-FI items. Content validity was assessed by comparing the GBD-FI with a selection of established FIs. Properties including the rate of deficit accumulation with age were examined to assess construct validity. Linear regression models were created to asse

SUBMITTER: O'Donovan M 

PROVIDER: S-EPMC7460080 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature