Genetic Variability in the Italian Heavy Draught Horse from Pedigree Data and Genomic Information.

ABSTRACT: This study aimed to investigate the genetic diversity in the Italian Heavy Horse Breed from pedigree and genomic data. Pedigree information for 64,917 individuals were used to assess inbreeding level, effective population size (Ne), and effective numbers of founders and ancestors (f_a/f_e). Genotypic information from SNP markers were available for 267 individuals of both sexes, and it allowed estimating genomic inbreeding in two methods (observed versus expected homozygosity and from ROH) to study the breed genomic structure and possible selection signatures. Pedigree and genomic inbreeding were greatly correlated (0.65 on average). The inbreeding trend increased over time, apart from periods in which the base population enlarged, when Ne increased also. Recent b

SUBMITTER: Mancin E 

PROVIDER: S-EPMC7460293 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature